Location
gurugram
Search

TPMT (Thio Purine Methyl Transferase) Gene

discountup to 50% off
Home
arrow
Tests
arrow
TPMT (Thio Purine Methyl Transferase) Gene
background
discountup to 50% off

TPMT (Thio Purine Methyl Transferase) Gene, in Mumbai

TPMT (Thio Purine Methyl Transferase) Gene in Chembur, Mumbai: The TPMT gene test checks for changes in the TPMT gene that influence TPMT enzyme activity. Book with GetVisit for NABL-accredited results, same-day slots, home collection and cashless OPD.

centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
customers
20K+Customers
certified
CertifiedLabs
rating
4.5+Rating
proven
ProvenAccuracy

What is a TPMT (Thio Purine Methyl Transferase) Gene Test in Mumbai ?

What is TPMT (Thio Purine Methyl Transferase) Gene?

The TPMT gene test checks for changes in the TPMT gene that influence TPMT enzyme activity. This enzyme helps break down thiopurine medicines such as azathioprine, mercaptopurine, and thioguanine. A single blood draw provides objective data on oxygen-carrying capacity, immune status, platelet function, and iron utilisation , making it one of the most informative single tests in clinical medicine.

What does TPMT (Thio Purine Methyl Transferase) Gene measure?

When enzyme activity is low, these drugs can build up and cause serious bone marrow suppression. Testing helps predict who is at higher risk of very low blood counts and severe side effects. Doctors use results to choose safer drugs or lower starting doses. The test is helpful in cancer care, gastroenterology for inflammatory bowel disease, and rheumatology.

What symptoms suggest TPMT (Thio Purine Methyl Transferase) Gene may be needed?

A doctor may recommend TPMT (Thio Purine Methyl Transferase) Gene when a patient reports persistent fatigue or weakness, pallor (pale skin or inner eyelids), shortness of breath on mild exertion, dizziness, frequent infections, unexplained bruising or bleeding, and swollen lymph nodes. In Mumbai, you can book this test online with home collection available in Powai, Lower Parel, and beyond.

How is TPMT (Thio Purine Methyl Transferase) Gene performed?

Collection is a routine blood draw. Using a single-use sterile needle, the phlebotomist takes a small sample from a vein in your arm; GetVisit's team in Powai and Lower Parel, Mumbai then barcodes and transports it under controlled conditions to the NABL lab.

How accurate is TPMT (Thio Purine Methyl Transferase) Gene?

Results are analytically reliable because GetVisit's Mumbai logistics network maintains proper cold-chain transport from your Powai or Lower Parel collection point to the processing lab, preserving sample integrity. NABL independently audits quality control at regular intervals.

Are there any risks to TPMT (Thio Purine Methyl Transferase) Gene?

Beyond a brief pinch, TPMT (Thio Purine Methyl Transferase) Gene carries almost no risk. Keep the arm relaxed during the draw, press gently on the site afterwards, and avoid heavy lifting with that arm for about an hour.

Did you know?

The TPMT blood test measures activity or genetic variants of thiopurine S‑methyltransferase to predict how a patient will metabolize thiopurine drugs (azathioprine, 6‑mercaptopurine, thioguanine).

TPMT (Thio Purine Methyl Transferase) Gene Test Preparation in Mumbai

Fasting instructions:

Eat and drink as you normally would; fasting is not required. Try to avoid a very fatty meal or alcohol right before the appointment.

What to bring along:

Keep your prescription and ID handy, along with your OPD insurance details if applicable. Wear sleeves that roll up easily.

Managing medication:

Skip iron, B12, or folate supplements on the morning of the test, as a recent dose can mask a true deficiency. Tell the staff if you take blood thinners.

Timing:

Book whenever is convenient; for fasting or hormone tests an early-morning slot is ideal. GetVisit covers Santacruz, Belapur, and all of Mumbai.

TPMT (Thio Purine Methyl Transferase) Gene Test Parameters in Mumbai

Single standalone test:

TPMT (Thio Purine Methyl Transferase) Gene. Can be ordered individually or as part of a preventive health package on GetVisit.

Why Take a TPMT (Thio Purine Methyl Transferase) Gene Test in Mumbai ?

When does a doctor order TPMT (Thio Purine Methyl Transferase) Gene?

TPMT (Thio Purine Methyl Transferase) Gene is usually offered as part of a pharmacogenetic panel before starting thiopurine drugs used in cancer, inflammatory bowel disease, or autoimmune conditions. Your doctor may order it if you had severe blood count drops or unexpected side effects from these medicines.

Who should get TPMT (Thio Purine Methyl Transferase) Gene done in Mumbai?

Mumbai's 21 million metropolitan population, annual monsoon flooding creating severe leptospirosis and dengue risk in Kurla, Andheri, and Ghatkopar, high corporate stress and commute burden, significant diabetes and cardiovascular disease prevalence, and a massive working population with irregular meal and sleep patterns make regular preventive diagnostic testing an essential health investment for all residents. Blood-count testing benefits anyone with fatigue, pallor, or frequent infections, menstruating and pregnant women prone to anaemia, and patients on medication that affects the bone marrow. In Mumbai, iron and B12 deficiency anaemia are common, particularly among women and those on vegetarian diets in Belapur, Thane, and surrounding areas.

What conditions can TPMT (Thio Purine Methyl Transferase) Gene help diagnose?

Genetic variants cause low or absent enzyme function, increasing toxicity risk. A family history of thiopurine sensitivity also supports testing.

What do TPMT (Thio Purine Methyl Transferase) Gene results mean?

Higher or positive results: High TPMT activity means your body rapidly inactivates thiopurine drugs (azathioprine, 6‑mercaptopurine). Lower or negative results: TPMT deficiency reduces metabolism of thiopurine drugs, causing buildup of toxic metabolites that often lead to severe bone marrow suppression (pancytopenia: leukopenia, anemia, thrombocytopenia), increasing infection and bleeding risk. Your doctor reads the value against the reference range on your report and your symptoms, and may repeat a borderline result to confirm it.

How often should TPMT (Thio Purine Methyl Transferase) Gene be repeated?

Healthy adults: as part of an annual health check. Patients with anaemia under treatment: every 4 to 12 weeks until corrected. Patients on chemotherapy or marrow-affecting drugs: as frequently as their specialist directs, sometimes weekly. Pre-surgical patients: as part of standard clearance.

What happens after TPMT (Thio Purine Methyl Transferase) Gene results are ready?

You will be notified the moment results are ready, usually the same day for routine tests. Open the report in the GetVisit app to see each value beside its reference range, share it with your doctor in a tap, or book a specialist consultation to talk it through.

H

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

step-image
arrow-right

Select a Lab

Choose your preferred labs from top trusted partners

step-image
arrow-right

Select Date & Slot

Select a convenient date and time for your test

step-image
arrow-right

Pay & Book

Make payment and get confirmation within 2 hours

step-image

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is the TPMT blood test for?plus

The TPMT blood test measures activity or genetic variants of thiopurine S‑methyltransferase to predict how a patient will metabolize thiopurine drugs (azathioprine, 6‑mercaptopurine, thioguanine). It identifies people at higher risk for severe bone marrow suppression and infections, allowing dose adjustment or alternative therapy. Testing helps personalize treatment and reduce risk of dangerous blood‑count toxicity.

What is a TPMT test for Crohn's disease?plus

A TPMT test measures activity or genetic variants of the thiopurine methyltransferase enzyme before using thiopurine drugs (azathioprine, 6‑mercaptopurine) for Crohn’s disease. It identifies people at risk of severe bone marrow suppression who need lower doses or alternative therapy. It’s done by blood enzyme assay or genetic test; normal results still require routine blood monitoring during treatment.

What is the function of the TPMT gene?plus

The TPMT gene encodes the enzyme thiopurine S‑methyltransferase, which metabolizes and inactivates thiopurine drugs (e.g. azathioprine, 6‑mercaptopurine). Variants that reduce TPMT activity cause accumulation of toxic thioguanine nucleotides, raising the risk of severe myelosuppression and other adverse effects. Genetic or enzyme testing guides thiopurine dosing to improve efficacy and reduce toxicity.

What does TPMT deficiency cause?plus

TPMT deficiency reduces metabolism of thiopurine drugs, causing buildup of toxic metabolites that often lead to severe bone marrow suppression (pancytopenia: leukopenia, anemia, thrombocytopenia), increasing infection and bleeding risk. It also raises hepatotoxicity risk. Homozygous deficiency carries the greatest danger; heterozygotes have intermediate risk and usually need lower thiopurine doses or alternatives.

Do I need a doctor's prescription to book TPMT (Thio Purine Methyl Transferase) Gene?plus

You can book TPMT (Thio Purine Methyl Transferase) Gene on GetVisit with or without a prescription, though a doctor's advice helps with interpreting the result. Cashless OPD may require a referral, depending on your insurer.

Can TPMT (Thio Purine Methyl Transferase) Gene be combined with a health package?plus

Yes. TPMT (Thio Purine Methyl Transferase) Gene can be booked on its own or as part of a broader preventive health package on GetVisit, which often works out more cost-effective. You can choose either option before payment.

Visit Health Experience

End-to-end care delivered at the right time through our nationwide network

5,000+

Hospitals/Clinics

Tick India's most trusted health centres
Tick Optional 'You Book, Visit Pays' feature
Tick Cashless coverage from metro to rural
Visit Health Logo
Hospitals/Clinics

65,000+

Doctors & Specialists

Tick Priority access & same-day care
Tick Cashless in 1250+ cities
Tick Custom doctor onboarding
Doctors & Specialists
Doctors & Specialists

7,800+

Diagnostics Partners

Tick NABL-accredited labs
Tick Hassle-free sample collection
Tick Seamless report & prescription tracking
Diagnostics Partners
Diagnostics Partners

19,000+

Pharmacy Delivery Pincodes

Tick Home delivery & store pickup options
Tick End-to-end order tracking
Tick Auto-refills for regular medications
Pharmacy Delivery Pincodes
Pharmacy Delivery Pincodes

Your Care, Our Commitment!

More than 12,000 people trust us with their health

starstarstarstarstar

Something my doctor recommended at my last visit. GetVisit had same-day slots available which was really helpful in Andheri. Everything was hygienic and the staff clearly knew what they were doing. Simple blood test , nothing to be anxious about. Glad I did this , the result changed my doctor's approach to my treatment. Saved time and money compared to going to a hospital lab.

Sanjay Pawar

Mumbai

starstarstarstarstar

My doctor thought it was a good idea and I agreed. GetVisit showed prices upfront so I knew exactly what I was paying near Colaba. Simple blood test , nothing to be anxious about. My doctor said the report format was comprehensive and clear. Already recommended this to colleagues in my office.

Rajesh Yadav

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. No crowding, no chaos , a very different experience from hospital lab queues. I received the report on my phone and shared it directly with my doctor. The test confirmed exactly what my doctor had suspected. Great experience overall. Makes healthcare feel accessible.

Rukhsar Siddiqui

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. GetVisit listed multiple labs near me so I could choose the most convenient one in Dadar West. No crowding, no chaos , a very different experience from hospital lab queues. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Genuinely impressed with the service.

Hemant Deshpande

Mumbai

starstarstarstarstar

GetVisit showed prices upfront so I knew exactly what I was paying in Borivali West. Routine health monitoring , I do a full panel every year. The prick was barely noticeable. The test confirmed exactly what my doctor had suspected. Already told my family to book through GetVisit for their next tests.

Vikas Kumar

Mumbai

starstarstarstarstar

If you need a good diagnostic lab in Marine Lines, GetVisit is the easiest way to find and book one. My doctor thought it was a good idea and I agreed. I arrived and was attended to within ten minutes. The report had highlighted reference ranges which made it easy to read. Much better than queuing at a hospital lab.

Sushma Naik

Mumbai

starstarstarstarstar

The booking was smooth , I've used GetVisit twice now and it's always quick near my office in Andheri West. My office health camp flagged this and my doctor confirmed I should do it. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Aparna Kadam

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. Everything was hygienic and the staff clearly knew what they were doing. I received the report on my phone and shared it directly with my doctor. The report gave my doctor everything needed to make a confident diagnosis. Saved time and money compared to going to a hospital lab.

Rehana Patel

Mumbai

starstarstarstarstar

Part of my annual preventive health check. Simple blood test , nothing to be anxious about. GetVisit had a lab literally two minutes from my building , perfect in Chembur. The report had highlighted reference ranges which made it easy to read. Excellent service , especially helpful given how busy life gets in Mumbai.

Kavita Deshmukh

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. The phlebotomist was skilled and the draw was quick and painless. The report was detailed with clear reference ranges marked. Everything was within range , gave me real peace of mind. Already told my family to book through GetVisit for their next tests.

Natasha Pinto

Mumbai

starstarstarstarstar

Something my doctor recommended at my last visit. GetVisit had same-day slots available which was really helpful in Andheri. Everything was hygienic and the staff clearly knew what they were doing. Simple blood test , nothing to be anxious about. Glad I did this , the result changed my doctor's approach to my treatment. Saved time and money compared to going to a hospital lab.

Sanjay Pawar

Mumbai

starstarstarstarstar

My doctor thought it was a good idea and I agreed. GetVisit showed prices upfront so I knew exactly what I was paying near Colaba. Simple blood test , nothing to be anxious about. My doctor said the report format was comprehensive and clear. Already recommended this to colleagues in my office.

Rajesh Yadav

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. No crowding, no chaos , a very different experience from hospital lab queues. I received the report on my phone and shared it directly with my doctor. The test confirmed exactly what my doctor had suspected. Great experience overall. Makes healthcare feel accessible.

Rukhsar Siddiqui

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. GetVisit listed multiple labs near me so I could choose the most convenient one in Dadar West. No crowding, no chaos , a very different experience from hospital lab queues. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Genuinely impressed with the service.

Hemant Deshpande

Mumbai

starstarstarstarstar

GetVisit showed prices upfront so I knew exactly what I was paying in Borivali West. Routine health monitoring , I do a full panel every year. The prick was barely noticeable. The test confirmed exactly what my doctor had suspected. Already told my family to book through GetVisit for their next tests.

Vikas Kumar

Mumbai

starstarstarstarstar

If you need a good diagnostic lab in Marine Lines, GetVisit is the easiest way to find and book one. My doctor thought it was a good idea and I agreed. I arrived and was attended to within ten minutes. The report had highlighted reference ranges which made it easy to read. Much better than queuing at a hospital lab.

Sushma Naik

Mumbai

starstarstarstarstar

The booking was smooth , I've used GetVisit twice now and it's always quick near my office in Andheri West. My office health camp flagged this and my doctor confirmed I should do it. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Aparna Kadam

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. Everything was hygienic and the staff clearly knew what they were doing. I received the report on my phone and shared it directly with my doctor. The report gave my doctor everything needed to make a confident diagnosis. Saved time and money compared to going to a hospital lab.

Rehana Patel

Mumbai

starstarstarstarstar

Part of my annual preventive health check. Simple blood test , nothing to be anxious about. GetVisit had a lab literally two minutes from my building , perfect in Chembur. The report had highlighted reference ranges which made it easy to read. Excellent service , especially helpful given how busy life gets in Mumbai.

Kavita Deshmukh

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. The phlebotomist was skilled and the draw was quick and painless. The report was detailed with clear reference ranges marked. Everything was within range , gave me real peace of mind. Already told my family to book through GetVisit for their next tests.

Natasha Pinto

Mumbai

starstarstarstarstar

Something my doctor recommended at my last visit. GetVisit had same-day slots available which was really helpful in Andheri. Everything was hygienic and the staff clearly knew what they were doing. Simple blood test , nothing to be anxious about. Glad I did this , the result changed my doctor's approach to my treatment. Saved time and money compared to going to a hospital lab.

Sanjay Pawar

Mumbai

starstarstarstarstar

My doctor thought it was a good idea and I agreed. GetVisit showed prices upfront so I knew exactly what I was paying near Colaba. Simple blood test , nothing to be anxious about. My doctor said the report format was comprehensive and clear. Already recommended this to colleagues in my office.

Rajesh Yadav

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. No crowding, no chaos , a very different experience from hospital lab queues. I received the report on my phone and shared it directly with my doctor. The test confirmed exactly what my doctor had suspected. Great experience overall. Makes healthcare feel accessible.

Rukhsar Siddiqui

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. GetVisit listed multiple labs near me so I could choose the most convenient one in Dadar West. No crowding, no chaos , a very different experience from hospital lab queues. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Genuinely impressed with the service.

Hemant Deshpande

Mumbai

starstarstarstarstar

GetVisit showed prices upfront so I knew exactly what I was paying in Borivali West. Routine health monitoring , I do a full panel every year. The prick was barely noticeable. The test confirmed exactly what my doctor had suspected. Already told my family to book through GetVisit for their next tests.

Vikas Kumar

Mumbai

starstarstarstarstar

If you need a good diagnostic lab in Marine Lines, GetVisit is the easiest way to find and book one. My doctor thought it was a good idea and I agreed. I arrived and was attended to within ten minutes. The report had highlighted reference ranges which made it easy to read. Much better than queuing at a hospital lab.

Sushma Naik

Mumbai

starstarstarstarstar

The booking was smooth , I've used GetVisit twice now and it's always quick near my office in Andheri West. My office health camp flagged this and my doctor confirmed I should do it. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Aparna Kadam

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. Everything was hygienic and the staff clearly knew what they were doing. I received the report on my phone and shared it directly with my doctor. The report gave my doctor everything needed to make a confident diagnosis. Saved time and money compared to going to a hospital lab.

Rehana Patel

Mumbai

starstarstarstarstar

Part of my annual preventive health check. Simple blood test , nothing to be anxious about. GetVisit had a lab literally two minutes from my building , perfect in Chembur. The report had highlighted reference ranges which made it easy to read. Excellent service , especially helpful given how busy life gets in Mumbai.

Kavita Deshmukh

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. The phlebotomist was skilled and the draw was quick and painless. The report was detailed with clear reference ranges marked. Everything was within range , gave me real peace of mind. Already told my family to book through GetVisit for their next tests.

Natasha Pinto

Mumbai

starstarstarstarstar

Something my doctor recommended at my last visit. GetVisit had same-day slots available which was really helpful in Andheri. Everything was hygienic and the staff clearly knew what they were doing. Simple blood test , nothing to be anxious about. Glad I did this , the result changed my doctor's approach to my treatment. Saved time and money compared to going to a hospital lab.

Sanjay Pawar

Mumbai

starstarstarstarstar

My doctor thought it was a good idea and I agreed. GetVisit showed prices upfront so I knew exactly what I was paying near Colaba. Simple blood test , nothing to be anxious about. My doctor said the report format was comprehensive and clear. Already recommended this to colleagues in my office.

Rajesh Yadav

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. No crowding, no chaos , a very different experience from hospital lab queues. I received the report on my phone and shared it directly with my doctor. The test confirmed exactly what my doctor had suspected. Great experience overall. Makes healthcare feel accessible.

Rukhsar Siddiqui

Mumbai

starstarstarstarstar

Just staying on top of my health , something I started doing after turning 40. GetVisit listed multiple labs near me so I could choose the most convenient one in Dadar West. No crowding, no chaos , a very different experience from hospital lab queues. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Genuinely impressed with the service.

Hemant Deshpande

Mumbai

starstarstarstarstar

GetVisit showed prices upfront so I knew exactly what I was paying in Borivali West. Routine health monitoring , I do a full panel every year. The prick was barely noticeable. The test confirmed exactly what my doctor had suspected. Already told my family to book through GetVisit for their next tests.

Vikas Kumar

Mumbai

starstarstarstarstar

If you need a good diagnostic lab in Marine Lines, GetVisit is the easiest way to find and book one. My doctor thought it was a good idea and I agreed. I arrived and was attended to within ten minutes. The report had highlighted reference ranges which made it easy to read. Much better than queuing at a hospital lab.

Sushma Naik

Mumbai

starstarstarstarstar

The booking was smooth , I've used GetVisit twice now and it's always quick near my office in Andheri West. My office health camp flagged this and my doctor confirmed I should do it. Very quick blood draw and I was out in under fifteen minutes. My doctor was satisfied with the quality of the report. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Aparna Kadam

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. Everything was hygienic and the staff clearly knew what they were doing. I received the report on my phone and shared it directly with my doctor. The report gave my doctor everything needed to make a confident diagnosis. Saved time and money compared to going to a hospital lab.

Rehana Patel

Mumbai

starstarstarstarstar

Part of my annual preventive health check. Simple blood test , nothing to be anxious about. GetVisit had a lab literally two minutes from my building , perfect in Chembur. The report had highlighted reference ranges which made it easy to read. Excellent service , especially helpful given how busy life gets in Mumbai.

Kavita Deshmukh

Mumbai

starstarstarstarstar

My office health camp flagged this and my doctor confirmed I should do it. The phlebotomist was skilled and the draw was quick and painless. The report was detailed with clear reference ranges marked. Everything was within range , gave me real peace of mind. Already told my family to book through GetVisit for their next tests.

Natasha Pinto

Mumbai