Location
gurugram
Search

Scl-70 Antibody (Anti-Topoisomerase)

discountup to 50% off
Home
arrow
Tests
arrow
Scl-70 Antibody (Anti-Topoisomerase)
background
discountup to 50% off

Scl-70 Antibody (Anti-Topoisomerase), in Lucknow

Book Scl-70 Antibody (Anti-Topoisomerase) in Vibhuti Khand, Lucknow at GetVisit. The Scl-70 Antibody test measures antibodies against topoisomerase I, a protein found inside cells. NABL-accredited labs in Vibhuti Khand and Nishatganj, home collection, same-day results and cashless OPD.

centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
customers
20K+Customers
certified
CertifiedLabs
rating
4.5+Rating
proven
ProvenAccuracy

What is a Scl-70 Antibody (Anti-Topoisomerase) Test in Lucknow ?

What is Scl-70 Antibody (Anti-Topoisomerase)?

The Scl-70 Antibody test measures antibodies against topoisomerase I, a protein found inside cells. These antibodies form when the immune system attacks the body's own tissues. Physical examination provides clues; a test result removes ambiguity and allows targeted, evidence-based management to begin promptly.

What does Scl-70 Antibody (Anti-Topoisomerase) measure?

A positive result commonly points to systemic sclerosis (scleroderma), especially the diffuse type. It is linked to skin thickening and a higher chance of lung scarring (interstitial lung disease). Doctors use this test within an autoimmune or scleroderma panel. Results help support a diagnosis and guide monitoring and treatment.

What symptoms suggest Scl-70 Antibody (Anti-Topoisomerase) may be needed?

A doctor may recommend Scl-70 Antibody (Anti-Topoisomerase) when a patient reports any symptom your doctor has identified as requiring objective laboratory investigation , including unexplained fatigue, unexplained weight change, persistent pain, fever, or abnormal bleeding. Sample collection for Lucknow is available at labs and at home across Vibhuti Khand, Chinhat, and surrounding neighbourhoods.

How is Scl-70 Antibody (Anti-Topoisomerase) performed?

Collection is a routine blood draw. Using a single-use sterile needle, the phlebotomist takes a small sample from a vein in your arm; GetVisit's team in Vibhuti Khand and Chinhat, Lucknow then barcodes and transports it under controlled conditions to the NABL lab.

How accurate is Scl-70 Antibody (Anti-Topoisomerase)?

Every GetVisit sample from Vibhuti Khand, Chinhat, and across Lucknow is processed at NABL-accredited labs that use internationally calibrated reference standards, pass external quality assessments, and maintain internal quality control at every shift. Reports are accepted by all major hospital networks, specialists, and insurance providers in India.

Are there any risks to Scl-70 Antibody (Anti-Topoisomerase)?

A blood draw for Scl-70 Antibody (Anti-Topoisomerase) is very safe. Occasionally there is minor bruising or light-headedness; sitting for a couple of minutes afterwards at the Vibhuti Khand or Chinhat, Lucknow collection point usually prevents this.

Did you know?

Anti-topoisomerase I (anti‑Scl‑70) antibodies are autoantibodies directed against the nuclear enzyme topoisomerase I.

Scl-70 Antibody (Anti-Topoisomerase) Test Preparation in Lucknow

Fasting instructions:

There is no need to skip food or drink for this test. Staying well hydrated beforehand simply makes the sample easier to collect.

What to bring along:

Keep your prescription and ID handy, along with your OPD insurance details if applicable. Wear sleeves that roll up easily.

Managing medication:

Continue your regular medicines unless your doctor has told you otherwise.

Timing:

Choose a morning slot for the most consistent results. Same-day home collection is offered throughout Lucknow, Vibhuti Khand and Telibagh included.

Scl-70 Antibody (Anti-Topoisomerase) Test Parameters in Lucknow

Single standalone test:

Scl-70 Antibody (Anti-Topoisomerase). Can be ordered individually or as part of a preventive health package on GetVisit.

Why Take a Scl-70 Antibody (Anti-Topoisomerase) Test in Lucknow ?

When does a doctor order Scl-70 Antibody (Anti-Topoisomerase)?

Scl-70 Antibody (Anti-Topoisomerase) is usually ordered as part of a scleroderma or connective tissue autoimmune panel when patients have skin tightening, Raynaud's phenomenon, unexplained shortness of breath, or suspected organ fibrosis. It helps diagnose systemic sclerosis and predicts higher risk of lung and skin involvement.

Who should get Scl-70 Antibody (Anti-Topoisomerase) done in Lucknow?

Lucknow's growing population, rich Awadhi diet driving diabetes and heart disease, winter air pollution, and seasonal monsoon infections make regular preventive diagnostic testing worthwhile for residents across the city. Those who benefit most from regular Scl-70 Antibody (Anti-Topoisomerase) testing include adults above 40, people with sedentary lifestyles or BMI above 25, those managing chronic conditions, smokers, and anyone whose previous result was borderline. Early detection through regular testing in Lucknow is consistently more cost-effective than treating advanced disease.

What conditions can Scl-70 Antibody (Anti-Topoisomerase) help diagnose?

Abnormal results usually reflect autoimmune disease rather than lifestyle or medications. A family history of autoimmune disease may prompt earlier testing.

What do Scl-70 Antibody (Anti-Topoisomerase) results mean?

Higher or positive results: A positive anti‑Scl‑70 (anti–topoisomerase I) antibody suggests systemic sclerosis, particularly the diffuse cutaneous form. Your doctor reads the value against the reference range on your report and your symptoms, and may repeat a borderline result to confirm it.

How often should Scl-70 Antibody (Anti-Topoisomerase) be repeated?

For preventive screening with a normal baseline: annually for most adults above 35. For monitoring a known condition: at the interval your specialist recommends , typically every 3 to 6 months for active conditions and annually for stable, well-controlled ones.

What happens after Scl-70 Antibody (Anti-Topoisomerase) results are ready?

Results are delivered to your phone and stored securely on GetVisit. Any value the laboratory flags as critical is escalated for urgent review, and for everything else your doctor or a verified specialist can guide the next step at your convenience.

H

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

step-image
arrow-right

Select a Lab

Choose your preferred labs from top trusted partners

step-image
arrow-right

Select Date & Slot

Select a convenient date and time for your test

step-image
arrow-right

Pay & Book

Make payment and get confirmation within 2 hours

step-image

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is anti-topoisomerase I anti-SCL-70 antibodies?plus

Anti-topoisomerase I (anti‑Scl‑70) antibodies are autoantibodies directed against the nuclear enzyme topoisomerase I. They are a relatively specific blood marker for systemic sclerosis, particularly the diffuse cutaneous subtype, and are found in roughly 20–40% of affected people. Their presence correlates with greater skin involvement, higher risk of interstitial lung disease and pulmonary fibrosis, and generally indicates a more severe disease course.

What does a positive anti-Scl-70 mean?plus

A positive anti‑Scl‑70 (anti–topoisomerase I) antibody suggests systemic sclerosis, particularly the diffuse cutaneous form. It’s linked to more extensive skin involvement and higher risk of interstitial lung disease or pulmonary fibrosis, implying a potentially more severe course. It’s not diagnostic alone , clinical evaluation, pulmonary function tests, high‑resolution chest CT and rheumatology follow‑up are recommended.

What is the disease with anti-topoisomerase antibodies?plus

Anti-topoisomerase I (anti–Scl‑70) antibodies are classically associated with systemic sclerosis (scleroderma), particularly the diffuse cutaneous form. Their presence correlates with more extensive skin involvement, increased risk of interstitial lung disease/pulmonary fibrosis, and generally indicates a more severe disease course and poorer prognosis. They support diagnosis and help with risk stratification alongside clinical findings and other autoantibodies.

Can you have Scl-70 antibodies and not have scleroderma?plus

Yes , Scl‑70 (anti‑topoisomerase I) is strongly associated with systemic sclerosis but can occasionally be detected without clinical scleroderma. A positive result warrants clinical correlation, repeat testing and specialist assessment because it increases the likelihood of developing systemic sclerosis or overlap autoimmune disease. Evaluation typically includes an ANA panel, organ screening (pulmonary, cardiac/renal) and regular follow‑up.

Can Scl-70 Antibody (Anti-Topoisomerase) be combined with a health package?plus

Yes. Scl-70 Antibody (Anti-Topoisomerase) can be booked on its own or as part of a broader preventive health package on GetVisit, which often works out more cost-effective. You can choose either option before payment.

Can menstruation affect Scl-70 Antibody (Anti-Topoisomerase) results?plus

Some tests, such as iron studies and certain hormone panels, can be influenced by your menstrual cycle. If you are on your period, mention it so your doctor can judge whether timing matters for Scl-70 Antibody (Anti-Topoisomerase).

Visit Health Experience

End-to-end care delivered at the right time through our nationwide network

5,000+

Hospitals/Clinics

Tick India's most trusted health centres
Tick Optional 'You Book, Visit Pays' feature
Tick Cashless coverage from metro to rural
Visit Health Logo
Hospitals/Clinics

65,000+

Doctors & Specialists

Tick Priority access & same-day care
Tick Cashless in 1250+ cities
Tick Custom doctor onboarding
Doctors & Specialists
Doctors & Specialists

7,800+

Diagnostics Partners

Tick NABL-accredited labs
Tick Hassle-free sample collection
Tick Seamless report & prescription tracking
Diagnostics Partners
Diagnostics Partners

19,000+

Pharmacy Delivery Pincodes

Tick Home delivery & store pickup options
Tick End-to-end order tracking
Tick Auto-refills for regular medications
Pharmacy Delivery Pincodes
Pharmacy Delivery Pincodes

Your Care, Our Commitment!

More than 12,000 people trust us with their health

starstarstarstarstar

Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

Deloitte
starstarstarstar

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

HDFC Life
starstarstarstarstar

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

Deloitte
starstarstarstar

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

Deloitte
starstarstarstarstar

“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Deloitte
starstarstarstarstar

Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

Deepak kumar

Employee

Deloitte
starstarstarstarstar

Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

Deloitte
starstarstarstar

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

HDFC Life
starstarstarstarstar

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

Deloitte
starstarstarstar

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

Deloitte
starstarstarstarstar

“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Deloitte
starstarstarstarstar

Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

Deepak kumar

Employee

Deloitte
starstarstarstarstar

I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

reserveBank
starstarstarstar

Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

lic
starstarstarstar

“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

McKinsey
starstarstarstar

I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

Employee

Wipro
starstarstarstar

“Grateful to Shikhar for finding a cataract specialist at a convenient time and ensuring a smooth experience. A true asset to the Visit team!”

Shilpa Gupta

Employee

Wipro
starstarstarstar

Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee

adityaBirla
starstarstarstarstar

I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

reserveBank
starstarstarstar

Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

lic
starstarstarstar

“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

McKinsey
starstarstarstar

I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

Employee

Wipro
starstarstarstar

“Grateful to Shikhar for finding a cataract specialist at a convenient time and ensuring a smooth experience. A true asset to the Visit team!”

Shilpa Gupta

Employee

Wipro
starstarstarstar

Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee

adityaBirla