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Coombs Test - Direct, in Mumbai

The direct Coombs test looks for antibodies or complement proteins attached to red blood cells. Book Coombs Test - Direct in Malad, Mumbai at GetVisit, NABL labs in Malad and Powai, home collection, same-day results and cashless OPD.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
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Male/Female
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25 hours
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20K+Customers
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What is a Coombs Test - Direct Test in Mumbai ?

What is Coombs Test - Direct?

The direct Coombs test looks for antibodies or complement proteins attached to red blood cells. These immune markers can cause red cells to be destroyed faster than normal. It is one of the most commonly ordered blood tests worldwide and plays a key role in both preventive screening and the investigation of liver disease.

What does Coombs Test - Direct measure?

Detecting them helps identify immune-related hemolysis, which can lead to anemia, jaundice, and dark urine. Doctors use the test when there is unexplained anemia, a sudden drop in hemoglobin after transfusion, or newborn jaundice. It helps distinguish immune causes from other types of anemia and guides treatments such as steroids, immune-suppressing drugs, stopping an offending medication, or changing transfusion plans. The test is simple and done in a lab from a small blood sample.

What symptoms suggest Coombs Test - Direct may be needed?

A doctor may recommend Coombs Test - Direct when a patient reports fatigue or persistent low energy, yellowing of the skin or eyes (jaundice), dark amber or tea-coloured urine, pale or clay-coloured stools, upper right abdominal discomfort, nausea, loss of appetite, abdominal swelling, and unexplained weight loss. Sample collection for Mumbai is available at labs and at home across Vikhroli, Mulund, and surrounding neighbourhoods.

How is Coombs Test - Direct performed?

Collection is a routine blood draw. Using a single-use sterile needle, the phlebotomist takes a small sample from a vein in your arm; GetVisit's team in Vikhroli and Mulund, Mumbai then barcodes and transports it under controlled conditions to the NABL lab.

How accurate is Coombs Test - Direct?

Every GetVisit sample from Vikhroli, Mulund, and across Mumbai is processed at NABL-accredited labs that use internationally calibrated reference standards, pass external quality assessments, and maintain internal quality control at every shift. Reports are accepted by all major hospital networks, specialists, and insurance providers in India.

Are there any risks to Coombs Test - Direct?

Beyond a brief pinch, Coombs Test - Direct carries almost no risk. Keep the arm relaxed during the draw, press gently on the site afterwards, and avoid heavy lifting with that arm for about an hour.

Did you know?

The direct Coombs test (direct antiglobulin test) detects antibodies or complement already bound to a patient’s red blood cells.

Coombs Test - Direct Test Preparation in Mumbai

Managing medication:

Tell the collection staff about any prescription medicines, supplements, or herbal products you're using, and keep taking them unless advised otherwise.

Fasting instructions:

No special diet or fasting is needed. Carry on normally; just stay hydrated and avoid alcohol the night before.

Timing:

Book whenever is convenient; for fasting or hormone tests an early-morning slot is ideal. GetVisit covers Juhu, Kandivali, and all of Mumbai.

What to bring along:

Keep your prescription and ID handy, along with your OPD insurance details if applicable. Wear sleeves that roll up easily.

Coombs Test - Direct Test Parameters in Mumbai

Single standalone test:

Coombs Test - Direct. Can be ordered individually or as part of a preventive health package on GetVisit.

Why Take a Coombs Test - Direct Test in Mumbai ?

When does a doctor order Coombs Test - Direct?

Coombs Test - Direct is commonly included in hemolysis workups and blood bank testing when anemia, jaundice, dark urine, or a rapid drop in hemoglobin occurs. Doctors order it to diagnose autoimmune hemolytic anemia, evaluate transfusion reactions, newborn hemolysis, or drug-related hemolysis.

Who should get Coombs Test - Direct done in Mumbai?

Mumbai has among India's highest documented rates of alcohol consumption, contributing to a significant alcoholic liver disease burden across all socioeconomic groups. NAFLD is rising rapidly among the city's large corporate workforce in Lower Parel, Bandra-Kurla Complex, Worli, Powai, and Andheri West , driven by sedentary work, irregular eating patterns from long commutes, and high-calorie dining. NAFLD affects an estimated 25 to 35% of India's urban adults , the majority unaware. Regular liver testing in Mumbai's residential areas including Belapur and Vikhroli enables lifestyle intervention before irreversible scarring occurs. Patients recovering from hepatitis, those in alcohol recovery, and anyone with persistently unexplained fatigue also benefit from regular liver monitoring.

What conditions can Coombs Test - Direct help diagnose?

Abnormal results can come from autoimmune disease, certain medications, infections, or recent transfusions. A family history of hemolytic disorders may prompt earlier testing.

What do Coombs Test - Direct results mean?

Mildly elevated ALT or AST (2–3× normal): fatty liver, obesity, or medication effect , often reversible. Moderately elevated (3–10×): active viral hepatitis or drug toxicity , requires urgent investigation. Severely elevated (>10×): acute liver injury , a medical emergency. High bilirubin: liver processing failure, bile duct obstruction, or haemolysis. Low albumin: significant loss of liver synthetic function, seen in advanced cirrhosis or malnutrition.

How often should Coombs Test - Direct be repeated?

Adults with no liver risk factors and a previously normal result: annually. Patients with NAFLD or treated hepatitis: every 6 months. Patients on hepatotoxic medication: baseline before starting, then at 1 month, 3 months, and every 6 months during treatment. Patients with active liver disease: at intervals specified by their gastroenterologist.

What happens after Coombs Test - Direct results are ready?

Book a follow-up consultation after reviewing your results. GetVisit stores your reports alongside your previous test history, so your doctor sees your full health trend, not just today's snapshot. This longitudinal context significantly improves the clinical value of each repeat test.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is the direct Coombs test for?plus

The direct Coombs test (direct antiglobulin test) detects antibodies or complement already bound to a patient’s red blood cells. It is a laboratory test performed on a blood sample. It’s used to diagnose immune‑mediated hemolysis such as autoimmune hemolytic anemia, hemolytic transfusion reactions, hemolytic disease of the newborn and some drug‑induced hemolysis. A positive result supports immune‑driven RBC destruction and guides evaluation and treatment.

What does a positive Coombs test mean?plus

A positive Coombs test means antibodies or complement are attached to red blood cells, indicating an immune process against RBCs. This suggests immune-mediated hemolysis , causes include autoimmune hemolytic anemia, transfusion reactions, hemolytic disease of the newborn, or drug-induced hemolysis. A positive direct Coombs detects bound antibodies on a patient’s red cells; a positive indirect Coombs shows free antibodies in serum.

What is the difference between direct and indirect Coombs test?plus

The direct Coombs test detects antibodies or complement already bound to a patient’s red blood cells (in vivo), used to diagnose autoimmune hemolytic anemia, transfusion reactions, and hemolytic disease of the newborn. The indirect Coombs test detects free anti‑red‑cell antibodies in a patient’s serum (in vitro), used for antibody screening in blood typing, prenatal testing, and pre‑transfusion compatibility.

What to do if DCT is positive?plus

If a direct antiglobulin (DCT) test is positive, contact your clinician promptly. They’ll assess for hemolysis with CBC, reticulocyte count, bilirubin, LDH and peripheral smear, review medications and transfusion history, and test for autoimmune or drug-induced causes. Treatment may include stopping offending drugs, steroids or other immunosuppressants, transfusion if needed, and referral to a hematologist with close monitoring of hemoglobin, jaundice and renal function.

Can Coombs Test - Direct be combined with a health package?plus

Yes. Coombs Test - Direct can be booked on its own or as part of a broader preventive health package on GetVisit, which often works out more cost-effective. You can choose either option before payment.

Can I take my diabetes medication before Coombs Test - Direct?plus

If you take insulin or diabetes tablets and are fasting for Coombs Test - Direct, ask your doctor whether to delay the dose until after the sample is collected, to avoid a low-sugar episode.

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Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. No crowding, no chaos , a very different experience from hospital lab queues. Digital report on WhatsApp was convenient , my doctor reviewed it on the same call. The result was reassuring and we could move forward with the treatment plan. Already told my family to book through GetVisit for their next tests.

Sudhir Bhave

Mumbai

starstarstarstarstar

Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Everything was hygienic and the staff clearly knew what they were doing. Reports were sharp and detailed , no ambiguity in any of the values. The results were accurate and my doctor could take action immediately. Will book again without hesitation.

Abhijit Kadam

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. The GetVisit platform made it easy to pick a slot that worked for me near my office in Andheri West. Very quick blood draw and I was out in under fifteen minutes. Reports were sharp and detailed , no ambiguity in any of the values. Five stars , no complaints at all.

Ashwini Balse

Mumbai

starstarstarstarstar

My gastroenterologist wanted regular liver function monitoring. Found GetVisit online and the booking took under two minutes in Vikhroli. The lab staff were polite and I wasn't kept waiting. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Sanjiv Doshi

Mumbai

starstarstarstarstar

The lab staff were polite and I wasn't kept waiting. Keeping an eye on my liver after a hepatitis scare a couple of years ago. GetVisit had a lab literally two minutes from my building , perfect in Dadar. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Akash Singh

Mumbai

starstarstarstarstar

Found GetVisit online and the booking took under two minutes in Matunga. My gastroenterologist wanted regular liver function monitoring. Just a blood draw , over in two minutes. Based on this result, my treatment plan was updated. Five stars , no complaints at all.

Pallavi Tiwari

Mumbai

starstarstarstarstar

The report helped my doctor adjust my medication right away. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Kalyan. The technician was gentle , my elderly mother had no issues at all. Already recommended this to colleagues in my office.

Kavya Krishnaswamy

Mumbai

starstarstarstarstar

The whole thing was done from my phone in less than five minutes in Malad West. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. The prick was barely noticeable. The result was reassuring and we could move forward with the treatment plan. Already recommended this to colleagues in my office.

Viral Shah

Mumbai

starstarstarstarstar

Keeping an eye on my liver after a hepatitis scare a couple of years ago. Same-day report delivery , no need to go back and collect a paper copy. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Worli. The lab staff were polite and I wasn't kept waiting. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Zoya Rangwala

Mumbai

starstarstarstarstar

The report was detailed with clear reference ranges marked. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Found GetVisit online and the booking took under two minutes in Kurla. Everything was within range , gave me real peace of mind. Will book again without hesitation.

Darius Mistry

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. No crowding, no chaos , a very different experience from hospital lab queues. Digital report on WhatsApp was convenient , my doctor reviewed it on the same call. The result was reassuring and we could move forward with the treatment plan. Already told my family to book through GetVisit for their next tests.

Sudhir Bhave

Mumbai

starstarstarstarstar

Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Everything was hygienic and the staff clearly knew what they were doing. Reports were sharp and detailed , no ambiguity in any of the values. The results were accurate and my doctor could take action immediately. Will book again without hesitation.

Abhijit Kadam

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. The GetVisit platform made it easy to pick a slot that worked for me near my office in Andheri West. Very quick blood draw and I was out in under fifteen minutes. Reports were sharp and detailed , no ambiguity in any of the values. Five stars , no complaints at all.

Ashwini Balse

Mumbai

starstarstarstarstar

My gastroenterologist wanted regular liver function monitoring. Found GetVisit online and the booking took under two minutes in Vikhroli. The lab staff were polite and I wasn't kept waiting. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Sanjiv Doshi

Mumbai

starstarstarstarstar

The lab staff were polite and I wasn't kept waiting. Keeping an eye on my liver after a hepatitis scare a couple of years ago. GetVisit had a lab literally two minutes from my building , perfect in Dadar. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Akash Singh

Mumbai

starstarstarstarstar

Found GetVisit online and the booking took under two minutes in Matunga. My gastroenterologist wanted regular liver function monitoring. Just a blood draw , over in two minutes. Based on this result, my treatment plan was updated. Five stars , no complaints at all.

Pallavi Tiwari

Mumbai

starstarstarstarstar

The report helped my doctor adjust my medication right away. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Kalyan. The technician was gentle , my elderly mother had no issues at all. Already recommended this to colleagues in my office.

Kavya Krishnaswamy

Mumbai

starstarstarstarstar

The whole thing was done from my phone in less than five minutes in Malad West. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. The prick was barely noticeable. The result was reassuring and we could move forward with the treatment plan. Already recommended this to colleagues in my office.

Viral Shah

Mumbai

starstarstarstarstar

Keeping an eye on my liver after a hepatitis scare a couple of years ago. Same-day report delivery , no need to go back and collect a paper copy. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Worli. The lab staff were polite and I wasn't kept waiting. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Zoya Rangwala

Mumbai

starstarstarstarstar

The report was detailed with clear reference ranges marked. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Found GetVisit online and the booking took under two minutes in Kurla. Everything was within range , gave me real peace of mind. Will book again without hesitation.

Darius Mistry

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. No crowding, no chaos , a very different experience from hospital lab queues. Digital report on WhatsApp was convenient , my doctor reviewed it on the same call. The result was reassuring and we could move forward with the treatment plan. Already told my family to book through GetVisit for their next tests.

Sudhir Bhave

Mumbai

starstarstarstarstar

Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Everything was hygienic and the staff clearly knew what they were doing. Reports were sharp and detailed , no ambiguity in any of the values. The results were accurate and my doctor could take action immediately. Will book again without hesitation.

Abhijit Kadam

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. The GetVisit platform made it easy to pick a slot that worked for me near my office in Andheri West. Very quick blood draw and I was out in under fifteen minutes. Reports were sharp and detailed , no ambiguity in any of the values. Five stars , no complaints at all.

Ashwini Balse

Mumbai

starstarstarstarstar

My gastroenterologist wanted regular liver function monitoring. Found GetVisit online and the booking took under two minutes in Vikhroli. The lab staff were polite and I wasn't kept waiting. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Sanjiv Doshi

Mumbai

starstarstarstarstar

The lab staff were polite and I wasn't kept waiting. Keeping an eye on my liver after a hepatitis scare a couple of years ago. GetVisit had a lab literally two minutes from my building , perfect in Dadar. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Akash Singh

Mumbai

starstarstarstarstar

Found GetVisit online and the booking took under two minutes in Matunga. My gastroenterologist wanted regular liver function monitoring. Just a blood draw , over in two minutes. Based on this result, my treatment plan was updated. Five stars , no complaints at all.

Pallavi Tiwari

Mumbai

starstarstarstarstar

The report helped my doctor adjust my medication right away. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Kalyan. The technician was gentle , my elderly mother had no issues at all. Already recommended this to colleagues in my office.

Kavya Krishnaswamy

Mumbai

starstarstarstarstar

The whole thing was done from my phone in less than five minutes in Malad West. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. The prick was barely noticeable. The result was reassuring and we could move forward with the treatment plan. Already recommended this to colleagues in my office.

Viral Shah

Mumbai

starstarstarstarstar

Keeping an eye on my liver after a hepatitis scare a couple of years ago. Same-day report delivery , no need to go back and collect a paper copy. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Worli. The lab staff were polite and I wasn't kept waiting. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Zoya Rangwala

Mumbai

starstarstarstarstar

The report was detailed with clear reference ranges marked. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Found GetVisit online and the booking took under two minutes in Kurla. Everything was within range , gave me real peace of mind. Will book again without hesitation.

Darius Mistry

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. No crowding, no chaos , a very different experience from hospital lab queues. Digital report on WhatsApp was convenient , my doctor reviewed it on the same call. The result was reassuring and we could move forward with the treatment plan. Already told my family to book through GetVisit for their next tests.

Sudhir Bhave

Mumbai

starstarstarstarstar

Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Everything was hygienic and the staff clearly knew what they were doing. Reports were sharp and detailed , no ambiguity in any of the values. The results were accurate and my doctor could take action immediately. Will book again without hesitation.

Abhijit Kadam

Mumbai

starstarstarstarstar

Had some yellowing of the eyes during monsoon and my doctor sent me for this immediately. The GetVisit platform made it easy to pick a slot that worked for me near my office in Andheri West. Very quick blood draw and I was out in under fifteen minutes. Reports were sharp and detailed , no ambiguity in any of the values. Five stars , no complaints at all.

Ashwini Balse

Mumbai

starstarstarstarstar

My gastroenterologist wanted regular liver function monitoring. Found GetVisit online and the booking took under two minutes in Vikhroli. The lab staff were polite and I wasn't kept waiting. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Sanjiv Doshi

Mumbai

starstarstarstarstar

The lab staff were polite and I wasn't kept waiting. Keeping an eye on my liver after a hepatitis scare a couple of years ago. GetVisit had a lab literally two minutes from my building , perfect in Dadar. Reports were sharp and detailed , no ambiguity in any of the values. Much better than queuing at a hospital lab.

Akash Singh

Mumbai

starstarstarstarstar

Found GetVisit online and the booking took under two minutes in Matunga. My gastroenterologist wanted regular liver function monitoring. Just a blood draw , over in two minutes. Based on this result, my treatment plan was updated. Five stars , no complaints at all.

Pallavi Tiwari

Mumbai

starstarstarstarstar

The report helped my doctor adjust my medication right away. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Kalyan. The technician was gentle , my elderly mother had no issues at all. Already recommended this to colleagues in my office.

Kavya Krishnaswamy

Mumbai

starstarstarstarstar

The whole thing was done from my phone in less than five minutes in Malad West. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. The prick was barely noticeable. The result was reassuring and we could move forward with the treatment plan. Already recommended this to colleagues in my office.

Viral Shah

Mumbai

starstarstarstarstar

Keeping an eye on my liver after a hepatitis scare a couple of years ago. Same-day report delivery , no need to go back and collect a paper copy. With Mumbai traffic, finding a nearby lab through GetVisit was a relief in Worli. The lab staff were polite and I wasn't kept waiting. Highly recommend for anyone in Mumbai looking for reliable diagnostics.

Zoya Rangwala

Mumbai

starstarstarstarstar

The report was detailed with clear reference ranges marked. Fatigue and mild nausea , the doctor suspected the liver and ordered this right away. Found GetVisit online and the booking took under two minutes in Kurla. Everything was within range , gave me real peace of mind. Will book again without hesitation.

Darius Mistry

Mumbai