What is the normal range for CD58 (PNH Marker)?

Reference ranges for CD58 (PNH Marker) are determined by the laboratory based on values measured in healthy populations and are printed alongside your result on the report. Your doctor will explain whether your result is within normal limits, borderline, or significantly abnormal, and advise on what action, if any, is clinically indicated.

Do I need to fast before CD58 (PNH Marker)?

Fasting requirements depend on the specific test. Your doctor will advise when they order it. As a general precaution, avoid alcohol, a heavy meal, and strenuous exercise the evening before any blood test. If fasting is required, it is typically 8 to 12 hours with water freely allowed throughout.

Can I take my regular medication before CD58 (PNH Marker)?

For most tests, continue taking all prescribed medication as usual unless your doctor has specifically asked you to stop. Some medications alter specific marker levels and may affect interpretation. Always inform lab staff about all medications, supplements, and herbal remedies you are taking when you arrive for the test.

Can I book CD58 (PNH Marker) without a doctor's prescription on GetVisit?

Yes. Most standard diagnostic tests on GetVisit can be self-booked without a prescription. However, your results should be reviewed by a doctor who can interpret them in the context of your symptoms and health history. GetVisit also offers post-report consultations with verified specialists if you need guidance on your results.

Does GetVisit accept health insurance for CD58 (PNH Marker)?

Yes. GetVisit accepts cashless OPD benefits from HDFC ERGO, ICICI Lombard, and Niva Bupa for eligible tests including CD58 (PNH Marker). If your employer provides a corporate health plan with any of these insurers, you can use your benefit directly , no upfront payment required. Confirm coverage availability when booking.

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CD58 (PNH Marker), in Patna

This test measures the amount of CD58 protein on the surface of blood cells. Book CD58 (PNH Marker) in Exhibition Road, Patna at GetVisit, NABL labs in Exhibition Road and Danapur, home collection, same-day results and cashless OPD.

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Blood

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Male/Female

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What is a CD58 (PNH Marker) Test in Patna ?

What is CD58 (PNH Marker)?

This test measures the amount of CD58 protein on the surface of blood cells. CD58 helps immune cells recognize and talk to each other. Physical examination provides clues; a test result removes ambiguity and allows targeted, evidence-based management to begin promptly.

What does CD58 (PNH Marker) measure?

Measuring CD58 can reveal abnormal or missing surface proteins on blood cells. Such changes may appear in paroxysmal nocturnal hemoglobinuria (PNH) and related bone marrow disorders. Doctors use CD58 together with other flow cytometry markers to help diagnose PNH, to check how active the disease is, and to monitor response to treatment. The test can be useful when someone has unexplained anemia, dark urine, or unusual blood clots.

What symptoms suggest CD58 (PNH Marker) may be needed?

A doctor may recommend CD58 (PNH Marker) when a patient reports any symptom your doctor has identified as requiring objective laboratory investigation, including unexplained fatigue, unexplained weight change, persistent pain, fever, or abnormal bleeding. GetVisit makes testing convenient in Patna, with lab slots and home collection in Exhibition Road, Danapur, and nearby areas.

How is CD58 (PNH Marker) performed?

You provide a urine sample rather than blood. Follow the container instructions for a clean mid-stream catch, avoid contamination from soap or toilet water, and submit it within two hours of collection at a lab in Exhibition Road or via home pickup in Danapur, Patna. GetVisit handles labelling and NABL lab dispatch.

How accurate is CD58 (PNH Marker)?

GetVisit's NABL-accredited labs serving Exhibition Road and Danapur, Patna process urine samples on calibrated analysers under strict quality control. Accuracy depends on a clean mid-stream sample delivered promptly, so following the collection instructions is important. Reports are accepted by hospitals, specialists, and insurers across India.

Are there any risks to CD58 (PNH Marker)?

There is no medical risk. Providing a urine sample is completely non-invasive, with no needle and no discomfort. The only thing to get right is a clean collection: follow the container instructions to avoid contamination that could affect the result. Home collection in Exhibition Road or Danapur, Patna is just as safe as visiting a lab.

Did you know?

PNH markers include flow cytometry demonstrating absent or reduced GPI‑anchored proteins (CD55 and CD59) on red cells and granulocytes.

CD58 (PNH Marker) Test Preparation in Patna

Medication:

Unless your physician advises a change, keep taking your usual prescriptions as normal.

Fasting and diet:

Collect a clean-catch mid-stream sample in the container provided, ideally the first urine of the morning, and hand it in promptly for the most reliable result.

Timing and slots:

Book whenever is convenient; for fasting or hormone tests an early-morning slot is ideal. GetVisit covers Khagaul, Anisabad, and all of Patna.

What to bring:

Have your doctor's referral and photo ID ready; earlier reports for the same test are useful for tracking trends.

CD58 (PNH Marker) Test Parameters in Patna

Single standalone test:

CD58 (PNH Marker). Can be ordered individually or as part of a preventive health package on GetVisit.

Why Take a CD58 (PNH Marker) Test in Patna ?

When does a doctor order CD58 (PNH Marker)?

CD58 (PNH Marker) is usually part of a flow cytometry panel used to evaluate suspected PNH or related bone marrow disorders. Doctors may order it when a patient has unexplained anemia, fatigue, dark urine, or blood clots.

Who should get CD58 (PNH Marker) done in Patna?

Patna's Ganga floodplain geography and monsoon waterborne-infection burden, widespread iron and vitamin deficiency, rising diabetes and cardiovascular disease, and hot summers make regular preventive diagnostic testing especially valuable for residents across the city. Adults above 30 in Patna benefit from periodic health screening that includes CD58 (PNH Marker) as part of a broader preventive panel. Residents of Exhibition Road, Danapur, and across the city with chronic conditions, those on long-term medication, and individuals with a relevant family history should test at the frequency their specialist recommends.

What conditions can CD58 (PNH Marker) help diagnose?

The test helps detect blood cell clones that lack normal surface proteins. Abnormal results most often reflect an acquired condition such as PNH rather than lifestyle causes. A family history of bone marrow disease or unexplained hemolysis may make testing more important.

What do CD58 (PNH Marker) results mean?

Higher or positive results: PNH is typically Coombs-negative. Lower or negative results: PNH is typically Coombs-negative. Your doctor reads the value against the reference range on your report and your symptoms, and may repeat a borderline result to confirm it.

How often should CD58 (PNH Marker) be repeated?

For preventive screening with a normal baseline: annually for most adults above 35. For monitoring a known condition: at the interval your specialist recommends, typically every 3 to 6 months for active conditions and annually for stable, well-controlled ones.

What happens after your CD58 (PNH Marker) results are ready?

Reports arrive digitally and remain in your GetVisit history, so repeat tests can be tracked over months and years. Review anything unexpected with your doctor before changing medication or lifestyle, and use the app to book a follow-up if needed.

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Frequently asked questions

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What are the markers for PNH?

PNH markers include flow cytometry demonstrating absent or reduced GPI‑anchored proteins (CD55 and CD59) on red cells and granulocytes. Laboratory evidence of hemolysis, elevated LDH, indirect bilirubin, reticulocytosis, low haptoglobin and hemoglobinuria, is typical. Historical sucrose lysis or Ham (acidified serum) tests may be positive. Patients may also show marrow abnormalities or thrombotic markers (e.g. elevated D‑dimer).

What is CD55 and CD59 in PNH?

CD55 (decay‑accelerating factor) and CD59 (protectin) are GPI‑anchored complement regulators on red blood cells. In PNH, PIGA gene-mediated loss of GPI anchors removes CD55 and CD59, allowing unchecked complement activation. CD55 disrupts C3/C5 convertases; CD59 prevents membrane attack complex formation. Their absence causes intravascular hemolysis, hemoglobinuria, anemia and fatigue, with increased thrombosis risk.

What is the gold standard for diagnosing PNH?

The gold standard for diagnosing paroxysmal nocturnal hemoglobinuria (PNH) is flow cytometry demonstrating absence or reduced expression of GPI‑anchored proteins (especially CD55 and CD59) on red blood cells and granulocytes. FLAER‑enhanced flow cytometry (using fluorescent aerolysin) provides higher sensitivity and is preferred for detecting PNH clones in granulocytes and monocytes, confirming diagnosis and guiding management.

Is PNH Coombs positive or negative?

PNH is typically Coombs-negative. Hemolysis is complement-mediated due to loss of GPI-anchored proteins (CD55/CD59) on red cells, causing intravascular destruction without autoantibodies. Therefore the direct antiglobulin (Coombs) test is usually negative. Rarely, concomitant autoimmune hemolysis can yield a positive Coombs, but classic PNH is diagnosed by flow cytometry showing CD55/CD59 deficiency.

Can I drink coffee or tea before CD58 (PNH Marker)?

If CD58 (PNH Marker) needs fasting, avoid tea and coffee (even without sugar) during the fasting window, as they can affect some results; plain water is fine. If no fasting is required, your usual drinks are okay.

Can CD58 (PNH Marker) be combined with a health package?

Yes. CD58 (PNH Marker) can be booked on its own or as part of a broader preventive health package on GetVisit, which often works out more cost-effective. You can choose either option before payment.

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A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

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A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

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Manager Administration

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