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CD58 (PNH Marker), in Lucknow

Looking for CD58 (PNH Marker) in Chowk, Lucknow? This test measures the amount of CD58 protein on the surface of blood cells. GetVisit offers verified NABL labs in Chowk and Chinhat, transparent pricing and home collection.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
28 hours
TEST INCLUDED
1
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20K+Customers
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What is a CD58 (PNH Marker) Test in Lucknow ?

What is CD58 (PNH Marker)?

This test measures the amount of CD58 protein on the surface of blood cells. CD58 helps immune cells recognize and talk to each other. Physical examination provides clues; a test result removes ambiguity and allows targeted, evidence-based management to begin promptly.

What does CD58 (PNH Marker) measure?

Measuring CD58 can reveal abnormal or missing surface proteins on blood cells. Such changes may appear in paroxysmal nocturnal hemoglobinuria (PNH) and related bone marrow disorders. Doctors use CD58 together with other flow cytometry markers to help diagnose PNH, to check how active the disease is, and to monitor response to treatment. The test can be useful when someone has unexplained anemia, dark urine, or unusual blood clots.

What symptoms suggest CD58 (PNH Marker) may be needed?

A doctor may recommend CD58 (PNH Marker) when a patient reports any symptom your doctor has identified as requiring objective laboratory investigation , including unexplained fatigue, unexplained weight change, persistent pain, fever, or abnormal bleeding. Sample collection for Lucknow is available at labs and at home across Sushant Golf City, Mahanagar, and surrounding neighbourhoods.

How is CD58 (PNH Marker) performed?

You provide a urine sample rather than blood. Follow the container instructions for a clean mid-stream catch, avoid contamination from soap or toilet water, and submit it within two hours of collection at a lab in Sushant Golf City or via home pickup in Mahanagar, Lucknow. GetVisit handles labelling and NABL lab dispatch.

How accurate is CD58 (PNH Marker)?

GetVisit's NABL-accredited labs serving Sushant Golf City and Mahanagar, Lucknow process urine samples on calibrated analysers under strict quality control. Accuracy depends on a clean mid-stream sample delivered promptly, so following the collection instructions is important. Reports are accepted by hospitals, specialists, and insurers across India.

Are there any risks to CD58 (PNH Marker)?

There is no medical risk. Providing a urine sample is completely non-invasive, with no needle and no discomfort. The only thing to get right is a clean collection: follow the container instructions to avoid contamination that could affect the result. Home collection in Sushant Golf City or Mahanagar, Lucknow is just as safe as visiting a lab.

Did you know?

PNH markers include flow cytometry demonstrating absent or reduced GPI‑anchored proteins (CD55 and CD59) on red cells and granulocytes.

CD58 (PNH Marker) Test Preparation in Lucknow

Your medicines:

There's usually no need to stop your regular medication; just let the staff know what you take.

Before you come:

Collect a clean-catch mid-stream sample in the container provided, ideally the first urine of the morning, and hand it in promptly for the most reliable result.

Booking your slot:

Morning appointments suit most tests, when the body's markers are most stable. GetVisit home collection in Lucknow starts at 6:00 AM, including Gomti Nagar and Hazratganj.

Documents and clothing:

Have your doctor's referral and photo ID ready; earlier reports for the same test are useful for tracking trends.

CD58 (PNH Marker) Test Parameters in Lucknow

Single standalone test:

CD58 (PNH Marker). Can be ordered individually or as part of a preventive health package on GetVisit.

Why Take a CD58 (PNH Marker) Test in Lucknow ?

When does a doctor order CD58 (PNH Marker)?

CD58 (PNH Marker) is usually part of a flow cytometry panel used to evaluate suspected PNH or related bone marrow disorders. Doctors may order it when a patient has unexplained anemia, fatigue, dark urine, or blood clots.

Who should get CD58 (PNH Marker) done in Lucknow?

Lucknow's growing population, rich Awadhi diet driving diabetes and heart disease, winter air pollution, and seasonal monsoon infections make regular preventive diagnostic testing worthwhile for residents across the city. Adults above 30 in Lucknow benefit from periodic health screening that includes CD58 (PNH Marker) as part of a broader preventive panel. Residents of Rajajipuram, Charbagh, and across the city with chronic conditions, those on long-term medication, and individuals with a relevant family history should test at the frequency their specialist recommends.

What conditions can CD58 (PNH Marker) help diagnose?

The test helps detect blood cell clones that lack normal surface proteins. Abnormal results most often reflect an acquired condition such as PNH rather than lifestyle causes. A family history of bone marrow disease or unexplained hemolysis may make testing more important.

What do CD58 (PNH Marker) results mean?

Higher or positive results: PNH is typically Coombs-negative. Lower or negative results: PNH is typically Coombs-negative. Your doctor reads the value against the reference range on your report and your symptoms, and may repeat a borderline result to confirm it.

How often should CD58 (PNH Marker) be repeated?

For preventive screening with a normal baseline: annually for most adults above 35. For monitoring a known condition: at the interval your specialist recommends , typically every 3 to 6 months for active conditions and annually for stable, well-controlled ones.

What happens after CD58 (PNH Marker) results are ready?

Once your results appear in your GetVisit profile, discuss them with your doctor or a GetVisit-verified specialist. Your doctor will interpret each value in the context of your full health history, current medications, and symptoms, and advise on the next step: lifestyle change, repeat testing, medication adjustment, or specialist referral. All GetVisit reports are stored permanently and can be shared with any doctor instantly.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What are the markers for PNH?plus

PNH markers include flow cytometry demonstrating absent or reduced GPI‑anchored proteins (CD55 and CD59) on red cells and granulocytes. Laboratory evidence of hemolysis, elevated LDH, indirect bilirubin, reticulocytosis, low haptoglobin and hemoglobinuria, is typical. Historical sucrose lysis or Ham (acidified serum) tests may be positive. Patients may also show marrow abnormalities or thrombotic markers (e.g. elevated D‑dimer).

What is CD55 and CD59 in PNH?plus

CD55 (decay‑accelerating factor) and CD59 (protectin) are GPI‑anchored complement regulators on red blood cells. In PNH, PIGA gene–mediated loss of GPI anchors removes CD55 and CD59, allowing unchecked complement activation. CD55 disrupts C3/C5 convertases; CD59 prevents membrane attack complex formation. Their absence causes intravascular hemolysis, hemoglobinuria, anemia and fatigue, with increased thrombosis risk.

What is the gold standard for diagnosing PNH?plus

The gold standard for diagnosing paroxysmal nocturnal hemoglobinuria (PNH) is flow cytometry demonstrating absence or reduced expression of GPI‑anchored proteins (especially CD55 and CD59) on red blood cells and granulocytes. FLAER‑enhanced flow cytometry (using fluorescent aerolysin) provides higher sensitivity and is preferred for detecting PNH clones in granulocytes and monocytes, confirming diagnosis and guiding management.

Is PNH Coombs positive or negative?plus

PNH is typically Coombs-negative. Hemolysis is complement-mediated due to loss of GPI-anchored proteins (CD55/CD59) on red cells, causing intravascular destruction without autoantibodies. Therefore the direct antiglobulin (Coombs) test is usually negative. Rarely, concomitant autoimmune hemolysis can yield a positive Coombs, but classic PNH is diagnosed by flow cytometry showing CD55/CD59 deficiency.

Do I need a doctor's prescription to book CD58 (PNH Marker)?plus

You can book CD58 (PNH Marker) on GetVisit with or without a prescription, though a doctor's advice helps with interpreting the result. Cashless OPD may require a referral, depending on your insurer.

Can I take my diabetes medication before CD58 (PNH Marker)?plus

If you take insulin or diabetes tablets and are fasting for CD58 (PNH Marker), ask your doctor whether to delay the dose until after the sample is collected, to avoid a low-sugar episode.

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