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CD55 (PNH Marker), in Lucknow

CD55 (PNH Marker) in Aliganj, Lucknow: The CD55 (PNH Marker) test measures the amount of CD55 protein on red blood cells. Book with GetVisit for NABL-accredited results, same-day slots, home collection and cashless OPD.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
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Male/Female
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25 hours
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What is a CD55 (PNH Marker) Test in Lucknow ?

What is CD55 (PNH Marker)?

The CD55 (PNH Marker) test measures the amount of CD55 protein on red blood cells. CD55 helps protect blood cells from the body's complement system, which can destroy cells if unchecked. Physical examination provides clues; a test result removes ambiguity and allows targeted, evidence-based management to begin promptly.

What does CD55 (PNH Marker) measure?

Low or absent CD55 is a hallmark of paroxysmal nocturnal hemoglobinuria (PNH). Detecting reduced CD55 helps explain unexplained anemia, dark urine, and unusual blood clots. Doctors use this test with other markers, like CD59, usually by flow cytometry. It helps confirm a PNH diagnosis, estimate the size of the affected cell population, and monitor response to treatments that block complement activity.

What symptoms suggest CD55 (PNH Marker) may be needed?

A doctor may recommend CD55 (PNH Marker) when a patient reports any symptom your doctor has identified as requiring objective laboratory investigation , including unexplained fatigue, unexplained weight change, persistent pain, fever, or abnormal bleeding. Sample collection for Lucknow is available at labs and at home across Indira Nagar, Aliganj, and surrounding neighbourhoods.

How is CD55 (PNH Marker) performed?

You provide a urine sample rather than blood. Follow the container instructions for a clean mid-stream catch, avoid contamination from soap or toilet water, and submit it within two hours of collection at a lab in Indira Nagar or via home pickup in Aliganj, Lucknow. GetVisit handles labelling and NABL lab dispatch.

How accurate is CD55 (PNH Marker)?

Urine results are reliable when the sample is collected cleanly and transported quickly. GetVisit's Lucknow network handles prompt, temperature-appropriate transport from Indira Nagar or Aliganj to the NABL lab, and quality control is independently audited by NABL.

Are there any risks to CD55 (PNH Marker)?

There is no medical risk. Providing a urine sample is completely non-invasive, with no needle and no discomfort. The only thing to get right is a clean collection: follow the container instructions to avoid contamination that could affect the result. Home collection in Indira Nagar or Aliganj, Lucknow is just as safe as visiting a lab.

Did you know?

CD59 is a GPI‑anchored complement regulatory protein on blood cell membranes that prevents formation of the membrane attack complex (C5b–C9).

CD55 (PNH Marker) Test Preparation in Lucknow

Fasting instructions:

Collect a clean-catch mid-stream sample in the container provided, ideally the first urine of the morning, and hand it in promptly for the most reliable result.

Managing medication:

Tell the collection staff about any prescription medicines, supplements, or herbal products you're using, and keep taking them unless advised otherwise.

What to bring along:

Keep your prescription and ID handy, along with your OPD insurance details if applicable. Wear sleeves that roll up easily.

Timing:

Morning appointments suit most tests, when the body's markers are most stable. GetVisit home collection in Lucknow starts at 6:00 AM, including Mahanagar and Alambagh.

CD55 (PNH Marker) Test Parameters in Lucknow

Single standalone test:

CD55 (PNH Marker). Can be ordered individually or as part of a preventive health package on GetVisit.

Why Take a CD55 (PNH Marker) Test in Lucknow ?

When does a doctor order CD55 (PNH Marker)?

CD55 (PNH Marker) is usually ordered as part of a hemolysis or PNH flow cytometry panel that also checks CD59 and other markers. Doctors may request it for unexplained anemia, dark or cola-colored urine, or unusual blood clots.

Who should get CD55 (PNH Marker) done in Lucknow?

Lucknow's growing population, rich Awadhi diet driving diabetes and heart disease, winter air pollution, and seasonal monsoon infections make regular preventive diagnostic testing worthwhile for residents across the city. Those who benefit most from regular CD55 (PNH Marker) testing include adults above 40, people with sedentary lifestyles or BMI above 25, those managing chronic conditions, smokers, and anyone whose previous result was borderline. Early detection through regular testing in Lucknow is consistently more cost-effective than treating advanced disease.

What conditions can CD55 (PNH Marker) help diagnose?

It helps diagnose and monitor paroxysmal nocturnal hemoglobinuria and related bone marrow disorders. Abnormal results come from loss of GPI-anchored proteins on blood cells due to acquired mutations and from disease activity; certain blood disorders or treatments can affect results. A family history of unexplained hemolysis or blood disorders may prompt testing.

What do CD55 (PNH Marker) results mean?

Results are interpreted in context, not in isolation. GetVisit shows your measured value next to the laboratory reference range, and your doctor reads it together with your clinical picture and any earlier results. See the FAQs below for what typical high or low values can mean for this test.

How often should CD55 (PNH Marker) be repeated?

For preventive screening with a normal baseline: annually for most adults above 35. For monitoring a known condition: at the interval your specialist recommends , typically every 3 to 6 months for active conditions and annually for stable, well-controlled ones.

What happens after CD55 (PNH Marker) results are ready?

Reports arrive digitally and remain in your GetVisit history, so repeat tests can be tracked over months and years. Review anything unexpected with your doctor before changing medication or lifestyle, and use the app to book a follow-up if needed.

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Frequently asked questions

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What is CD59 in PNH?plus

CD59 is a GPI‑anchored complement regulatory protein on blood cell membranes that prevents formation of the membrane attack complex (C5b–C9). In PNH, PIGA mutations cause loss of CD59 from red cells and other blood cells, permitting unchecked complement‑mediated intravascular hemolysis and increased thrombosis risk. Flow cytometry detects CD59 deficiency for diagnosis and guides complement‑inhibitor therapy.

What are the markers for PNH?plus

PNH is marked by loss of GPI-anchored proteins, particularly CD55 and CD59, on red cells and leukocytes, detected by flow cytometry (often using FLAER). Laboratory markers include intravascular hemolysis (hemoglobinuria, elevated LDH, low haptoglobin, indirect hyperbilirubinemia, reticulocytosis), cytopenias, and an increased tendency for thrombosis. Historic tests include sucrose lysis or Ham test, but flow cytometry is diagnostic.

What do CD55 and CD59 do?plus

CD55 (decay-accelerating factor) and CD59 (protectin) are membrane proteins that protect host cells from complement-mediated damage. CD55 disrupts formation and accelerates decay of C3/C5 convertases, limiting complement activation. CD59 prevents membrane attack complex formation by blocking C9 polymerization, avoiding cell lysis. Both are broadly expressed on blood cells and endothelium; loss increases complement-driven injury.

What is the gold standard test for PNH?plus

The gold standard test for paroxysmal nocturnal hemoglobinuria (PNH) is flow cytometry demonstrating deficiency of GPI‑anchored proteins on blood cells. Multiparameter flow cytometry uses antibodies to CD55 and CD59 and FLAER (which binds GPI anchors) on red cells, granulocytes, and monocytes to detect and quantify PNH clones with high sensitivity and specificity.

Do I need a doctor's prescription to book CD55 (PNH Marker)?plus

You can book CD55 (PNH Marker) on GetVisit with or without a prescription, though a doctor's advice helps with interpreting the result. Cashless OPD may require a referral, depending on your insurer.

Can menstruation affect CD55 (PNH Marker) results?plus

Some tests, such as iron studies and certain hormone panels, can be influenced by your menstrual cycle. If you are on your period, mention it so your doctor can judge whether timing matters for CD55 (PNH Marker).

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